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Exploring the Antimicrobial Properties potential of Lactobacillus Plantarum Postbiotic Engineering k-016

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  • Wong Jest Phia,
  • Noraina Muhamad Zakuan,
  • Latifah Saiful Yazan
Wong Jest Phia
Westwood Clinic, Pj Midtown, Sekseyn 13 Petaling Jaya, Selangor, Malaysia.
Noraina Muhamad Zakuan
Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor,
Bio
Latifah Saiful Yazan
Department of Biomedical Science, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor,
Bio
Published in : International Journal of Scientific Research and Management (IJSRM) , Vol. 12 No. 06 (2024)

Submission to VIJ 2024-06-06

Keywords

  • Cancer, Lactic acid bacteria, Metabolites, Immunity

Copyright (c) 2024 Wong Jest Phia, Noraina Muhamad Zakuan, Latifah Saiful Yazan

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Abstract

Bacteria and their metabolites are shown to be a potential therapeutic agent for cancer treatment. Much attention has been directed to Lactic acid bacteria (LAB) which exhibits several killing mechanisms via invasion and colonization of solid tumors. Discovery of the characteristics of postbiotic metabolites that exert the same probiotic effects has attracted immense attention towards anti-cancer effect. It is known that LAB improves health and composition of microbiota in the gut. Supplementation of LAB is proven to enhance the host immunity and modulation of the immune system to fight diseases including cancers. Lactobacillus plantarum is the LAB species isolated from Malaysian fermented food, Tapai Ubi which capable of producing bioactive metabolic products. In this review, the properties will be discussed including anti-microbial, anti-cancer and immunomodulatory effects. Overall, it would be beneficial to discover the potential effects of UL4-PPM to possibly serve as an alternative treatment for cancer.

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